Renshaw was named for Commander William B. Renshaw, killed in the Civil War aboard Westfield at Galveston. She was a Kearny-built near-sister of Philip (DD-498) and reached the Pacific in time for the Solomons, then Saipan and Tinian, where she closed the beach to fire star shell during a Japanese counterattack.
In November 1944, on an anti-shipping sweep west of Leyte, she and the destroyers Saufley (DD-465), Waller (DD-466), and Pringle (DD-477) caught a Japanese submarine on the surface, identified as I-46. They sank her with gunfire after she fired back with small guns. The division then made a high-speed run into Ormoc Bay after reported transports. On 21 February 1945, in the Mindanao Sea during the southern Philippines campaign, a torpedo from the midget submarine HA-84 hit her about ten feet below the waterline and flooded the firerooms. She survived and came home. Eight battle stars.
Converted for antisubmarine work, she recommissioned in June 1950 as DDE-499 and made two Korean tours and later Vietnam deployments. Five Korean battle stars and six for Vietnam. She was sold to Zidell Explorations in October 1970 and scrapped. Her bell is at the Portsmouth Naval Shipyard Museum.