Mustin, DD-413, was a Sims-class destroyer named for Captain Henry C. Mustin, an early naval aviator who piloted the first aircraft catapulted from a ship. Newport News Shipbuilding laid her down on 20 December 1937, launched her on 8 December 1938, Mrs. Lloyd M. Mustin sponsoring, and commissioned her on 16 September 1939, Lieutenant Commander James B. Freeman in command.
She was in overhaul at Boston on 7 December 1941 and went to sea the next day escorting battleships. She reached Pearl Harbor on 17 February 1942, escorted a merchantman to Midway, and sailed with Task Force 17 in the Hornet group from 17 August. On 26 October 1942, in the Battle of the Santa Cruz Islands, she rescued 337 of Hornet's survivors and then fired a full salvo of torpedoes at the abandoned carrier, which did not sink her. DANFS credits her with five enemy aircraft shot down in the battle.
She served in the Solomons and the Aleutians in 1943. For the Marshalls she reached Lahaina Roads on 21 January 1944, bombarded Wotje on 30 January, screened the cruisers that bombarded Kwajalein on 31 January, and fired on the atoll on 1 February. She then escorted task groups there for two weeks and operated off Eniwetok. She screened carriers at Aitape, Hollandia and Wakde, was fighter director at Morotai on 15 September 1944, and shot down three planes off Leyte on 27 November. She fired in support at Lingayen from 9 January 1945 and screened the transports at Okinawa from 1 April.
She was overhauled at San Pedro, reached Ominato, Honshu, for occupation duty in September 1945, and was a target at the Bikini tests in 1946. DANFS prints the year of her arrival at Ominato as 1946, which cannot be right, since the war ended before she left San Pedro. She was decommissioned on 29 August 1946 and destroyed by gunfire in the Marshalls on 18 April 1948. NavSource says scuttled off Kwajalein and struck on 30 April 1948. She earned 13 battle stars.