USS Radford (DD-446) was a Fletcher-class destroyer of the United States Navy. She was launched on 3 May 1942 and commissioned on 22 July 1942. William K. Romoser was her captain from the day she entered service.
She fought in the Battle of Kula Gulf on 6 July 1943. In that action she was stationed astern of the cruisers.
After the cruiser Helena sank, Radford stayed with the destroyer Nicholas. The two ships took off more than 700 of Helena's men.
Before dawn the same pair fired on the destroyer Mochizuki. Accounts of that firing differ on whether Mochizuki was hit.
On 25 November 1943, west of Makin, Radford depth-charged the submarine I-19. That boat was lost with all hands. Radford survived the war. She was sold for scrap in October 1970.
